• Knockout of Dnmta and Dnmt

  2018-10-29

  

  Knockout of Dnmta3 and Dnmt3b in ESCs leads to progressive hypomethylation, supporting the notion that de novo activity is required to maintain 5mC in ESCs, possibly to offset persistent 5hmC conversion (Chen et al., 2003). However, importantly, Dnmt3a/b null ESCs only exhibited an ∼10%–20% reductio

• currently The exogenous addition of osteogenically derived E

  2018-10-26

  

  The exogenous addition of osteogenically derived EVs outperformed the effect of current osteoinductive strategies in terms of the type and/or intensity of the signaling, with the early activation of the key osteogenic commitment genes SP7 (Figure 3B) and BMP2 (Figure 3C), considered necessary and su

• In BRGSKWv Wv mice the level of

  2018-10-26

  

  In BRGSKWv/Wv mice, the level of myeloid reconstitution was up to 30% and 60% at 8–12 weeks and 20–24 weeks after transplantation, respectively. These levels might be comparable with those in MITRG mice in which four critical myeloid cytokines were humanized (Rongvaux et al., 2014), although a direc

• By conditional ablation of Dicer specifically

  2018-10-26

  

  By conditional ablation of Dicer specifically in bona fide aNSCs of the adult hippocampus in vivo and in vitro and by manipulation of specific miRNAs, here we studied the role of miRNAs for lineage fate choice of aNSCs. Our study identified a set of 11 miRNAs that, by synergistic enforcement of gene

• In terms of chronic health profiles and epidemiological regi

  2018-10-26

  

  In terms of chronic health profiles and epidemiological regimes, the population in eastern Finland is similar to the forced migrants (Norio, 2003; Saarela and Finnäs, 2006). Cultural differences, which may affect health behaviours and diet, are also much less pronounced across Finnish regions than i

• To date the literature has been inconsistent regarding

  2018-10-26

  

  To date, the literature has been inconsistent regarding the direction of impact between weight perceptions and health behaviours. That is, no consensus has been reached on whether perceptions of being overweight – or underweight, for that pikfyve inhibitor – foster or discourage PA and healthy eati

• Finally gestation and early infancy

  2018-10-26

  

  Finally, jak stat pathway and early infancy are critical periods for health and overweight development in adolescence and adulthood (Currie & Almond, 2011; Dietz, 1994). To explore this association we ran models controlling for median income and mean education in the municipality at the time when e

• Methodological advances in bereavement research in recent ye

  2018-10-26

  

  Methodological advances in bereavement research in recent years have improved the quality of research outputs, not least through the introduction of the Integrated Risk Factor Framework (IRFF) (Stroebe, Folkman, Hansson, & Schut, 2006). A key feature of this framework is that variables from a number

• The remainder of the paper is organized as follows In

  2018-10-26

  

  The remainder of the paper is organized as follows. In Section 2, a review of the literature on the topic is presented. In Section 3, our methodology is explained and some data considerations are added. In Section 4, results are displayed and reflections per gender are offered. Section 5 discusses o

• The same jobs that have heavy

  2018-10-26

  

  The same jobs that have heavy physical work requirements may also have stressful psychosocial work conditions. Using national survey data from 27 European countries, Toch et al. (2014) examined the contribution of both physical and psychosocial work conditions to inequalities by social class categor

• The use of good quality instruments

  2018-10-26

  

  The use of good quality instruments is necessary when examining associations between adolescents’ neighbourhood social environments and their health and well-being. Different approaches are taken to conceptualisation, operationalisation and measurement which might explain inconsistent research findi

• More importantly as social and family

  2018-10-26

  

  More importantly, as social and family structures have changed rapidly, the living arrangements of older people are perceived as a dynamic process rather than a static status, which in turn may influence the adaptability to new circumstances, and thereby upon older people\'s mortality (Li and Li, 20

• Desde la perspectiva de los

  2018-10-26

  

  Desde la perspectiva de los países emergentes, es claro que las políticas y los problemas del Z DEVD FMK Mundo, unidos a los de orden nacional, crean una situación keynesiana de insuficiencia de la demanda que se refleja en el descenso de los ritmos de crecimiento de sus economías –China, India, Br

• br Las bases y los fundamentos de la intervenci

  2018-10-26

  

  Las bases y los fundamentos de la intervención pública en la actividad económica De manera específica, Kalecki argumentó que el sistema capitalista es inestable y provoca condiciones de subempleo porque no hay seguridad que el gasto capitalista (consumo e inversión privada) sea suficiente para em

• br Metodolog a Este trabajo busca demostrar

  2018-10-26

  

  Metodología Este trabajo busca demostrar el impacto de la ied en la distribución de empleos en los tres sectores de actividades de la economía mexicana. El análisis se realiza entre 1980 y 2014. Los datos provienen del inegi, Secretaría de Economía y Banxico. Para obtener resultados significativo

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