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protease activated receptor Our study has some limitations A
2018-10-25
Our study has some limitations. A potential shortcoming of our epitope mapping approach was lack of inclusion of variant peptides. Although our results are quite consistent with the comparable recognition of a larger panel of conserved and frequently occurring variant epitopes recently reported betw
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Another interesting implication of the work
2018-10-25
Another interesting implication of the work by Cartier and colleagues lies in unraveling the therapeutic potential of DA reverse transport in autism. Starting from the observation that rare autism-causing variants are associated with inhibition of reverse transport of DA, it could be hypothesized th
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Contrary to our results transient increases in
2018-10-25
Contrary to our results, transient increases in cardiac-specific troponin have been observed in 12–50% of patients following trastuzumab treatment, most frequently after the first cycle, and troponin-I was found to be the strongest independent predictor of cardiotoxicity in multivariate analyses (Ca
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Given that inflammation and telomere dependent cell
2018-10-25
Given that inflammation and telomere-dependent cell senescence can drive each other thus causing accelerated ageing (Jurk et al., 2014; Tchkonia et al., 2013), we were surprised to find evidence for inflammation as driver of ageing up to (semi-)supercentenarians, while telomere length/cell senescenc
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Finally in limited studies it has been suggested
2018-10-25
Finally, in limited studies it has been suggested that the presence or absence of any particular comorbid anxiety disorders may alter the pattern and prognosis of bipolar disorder. For instance, Pini et al. (1997) suggested three patterns in association with anxiety and affective disorder: (i) GAD w
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br Introduction Oral Oropharyngeal mucositis
2018-10-25
Introduction Oral/Oropharyngeal mucositis (OM) is probably the most common and debilitating complication that can occur during and shortly after radiotherapy and/or chemotherapy for patients with head-and-neck cancer (HNC). It is typically characterized by: erythema, edema, mucosal ulceration and
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Here we sought to characterize the contribution of
2018-10-25
Here we sought to characterize the contribution of DGKα and DGKζ to the generation of non-conventional bystander memory-like CD8+ T cell populations. We show that DGKζ deficiency, but not that of DGKα leads to increased output of CD44hiCD122hi CD8+ T bcr-abl tyrosine kinase inhibitors and facilitate
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br Acknowledgements br Data This data set contains tables
2018-10-25
Acknowledgements Data This data set contains 5 tables and 1 figure. Tables 1–3 represent the performance of R. maritima in saline wastewater treatment. Tables 4 and 5 show the specific growth rate and the nutrient uptake rate during the study, respectively. The photo of R. maritima plant is pr
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While many studies have now characterized the
2018-10-25
While many studies have now characterized the pattern of white flunixin meglumine changes over the course of development using age, very few have considered examining changes that coalesce with pubertal changes, rather than chronological age. One study (Asato et al., 2010) found that the vast majori
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Seldon has proposed that during human development white
2018-10-25
Seldon has proposed that during human development, white matter grows outward and expands to the overlying cortex similar to a balloon, affecting the capacity of the cortex (Seldon, 2005). The different rates of expansion in particular fatty acid amide hydrolase regions create regional differences
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Immediately after the recruitment of the
2018-10-25
Immediately after the recruitment of the right OFG, inhibitory-related tie2 processes to Angry faces activated the ventral part of the left anterior temporal pole (ATL) from 325 to 425ms, although this did not survive correction for multiple comparisons. However, this region of the ATL is known to
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The main limitation of this
2018-10-25
The main limitation of this study is that the Chinese version of the questionnaire adopted in this study has not been proved as a reliable and valid measure of eicosapentaenoic acid disease on the quality of life in Taiwanese/Chinese patients. Nonetheless, the interviewer who was a dermatologist pr
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A major scientific breakthrough came when a
2018-10-25
A major scientific breakthrough came when a China Lake researcher Nielsen synthesized the energetic solid HNIW [23]. The scale up method for the synthesis of HNIW was explained by Gore [24] and Latypov et al. [25]. The cage structure of HBIW is unstable due to oxidation via loss of two electrons by
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La homogeneidad entre participantes en los
2018-10-25
La homogeneidad entre participantes en los debates tiene consecuencias en cualquier campo de estudio. Uno de los efectos importantes es que permite que la mayoría de los médicos siga ignorando las implicaciones de su propia ubicación y perspectiva en su trabajo. Al igual que en otras disciplinas dom
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Tal vez por eso su fascinaci n con Salvador
2018-10-25
Tal vez por eso su fascinación con Salvador Novo. No lo dice abiertamente, pero creo que ve en él Ozanimod manufacturer un homosexual que se ha creado a sí mismo, desde la injuria y la burla, escarmentándose para refractar las risas que lo rodean sobre quienes las profieren. Novo, dice Monsiváis, “u
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