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En el Estudio preliminar el lector encontrar un magn
2019-04-16
En el “Estudio preliminar”, el lector encontrará un magnífico marco de referencia para ubicar con precisión la obra. Contra una vieja mala costumbre de la crítica mexicañista más convencional de repetir una y otra vez los juicios críticos de los grandes maestros, Belem Clark de Lara teje una trama m
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Further extensive FISH and molecular
2019-04-16
Further extensive FISH and molecular studies failed to detect either BCR–ABL, PDGFRA, PDGFRB and FGFR1 rearrangements or NPM1 and FLT3 mutations, whereas c-KIT D816V Puromycin was found on PB and BM mononuclear cells. Moreover, allele-specific PCR demonstrated JAK2 V617F mutation on both PB and BM
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In a revised consensus statement
2019-04-16
In 2012, a revised consensus statement for AF surgery was published by the Heart Rhythm Society/European Heart Rhythm Association/European Cardiac Arrhythmia Society as a part of the “Expert consensus statement for catheter and surgical ablation for AF” [7]. The statement was focused mainly on the r
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br Methods As we were not privy to the median
2019-04-16
Methods As we were not privy to the median year of enrolment, for all selected studies, the mean enrolment year ([start of enrolment+end of enrolment]/2) was calculated. If these dates were unavailable, the corresponding authors or sponsoring companies were contacted. When all methods to gather t
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Cell adhesion to extracellular matrix requires the interacti
2019-04-16
Cell adhesion to extracellular matrix requires the interaction of different molecules like selectins, cadherins and integrins [21]. Especially αvβ3 integrin has been proposed to mediate the adhesion of malignant cells in different entities such as multiple myeloma and breast cancer [22,23]. Upon ex
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According to the labeling of dabigatran
2019-04-16
According to the labeling of dabigatran in Japan, patients to be considered for the prescription of the lower dose of 220mg/day are as follows: (1) aged ≥70 years, (2) with moderate renal impairment (ClCr 30–50mL/min), (3) concomitant use of a p-glycoprotein inhibitor, and (4) history of hemorrhage
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br Conclusion br Financial support This research was support
2019-04-16
Conclusion Financial support This research was supported by a grant from the ׳Gerencia de Salud, Consejería de Sanidad, Junta de Castilla y Leon׳ [GRS 308/A/08] and ‘Caja Burgos Foundation’ [Convocatoria 2007].The funding organization had no involvement in the study. Clinical trial registra
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Sulfo-NHS-Biotin cost Cardiovascular magnetic resonance imag
2019-04-16
Cardiovascular magnetic resonance imaging (CMR) is recognized as a versatile, safe, and reproducible technique, allowing for accurate structural and functional assessment of the heart. CMR is the gold standard for ejection fraction measurement [15–17]. Considering the technical limitations of other
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br Bile acids as therapeutic
2019-04-16
Bile acids as therapeutic agents Conclusion Bile acids are important physiological agents for nutrient prostaglandin receptors and integrators of glucose, lipid, and energy metabolism control. Bile acid synthesis is tightly regulated to maintain metabolic homeostasis and prevent accumulation o
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Transformation of sanitation related knowledge into
2019-04-16
Transformation of sanitation-related knowledge into routine practice is hindered by traditional mindsets and the absence of awareness and an attitude to learn. Poverty has been described as a barrier to following safe hygiene practices. Regular use of footwear is equally important for the prevention
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The multivariable analyses by Keats and colleagues identifie
2019-04-15
The multivariable analyses by Keats and colleagues identified factors associated with higher coverage of key interventions in Kenya. Current and prospective efforts tracking key indicators and their determinants over time could enable time-series regression and more sophisticated causal inference an
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In order to treat metastatic bone disease
2019-04-15
In order to treat metastatic bone disease effectively all steps involved in the metastatic cascade need to be taken into account as for example the interactions between primary and secondary sites, tumour cell–bone cell cross talk and osteomimicri [8]. Therefore, concomitant targeting of both the tu
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The exact incidences of amiodarone induced hyperthyroidism a
2019-04-15
The exact incidences of amiodarone-induced hyperthyroidism and amiodarone-induced hypothyroidism currently remain unknown; however, the reported frequencies of amiodarone-induced hyperthyroidism and amiodarone-induced hypothyroidism vary widely from 0.8% to 37.8% [7–16] and from 1% to 32% [13,17–20]
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El an lisis de Close merece una continuaci n
2019-04-15
El análisis de Close merece una continuación. En efecto, la narrativa mexicana actual cuenta con otros autores de novelas de crímenes que se mantienen alejados de los tópicos necro-pornográficos misóginos y del gusto sensacionalista y moralista. En lo que sigue abogaremos por la inclusión de Alejand
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Antenatal corticosteroids induce fetal lung maturation throu
2019-04-15
Antenatal corticosteroids induce fetal lung maturation through the same biological mechanism in low-income settings as in high-income settings and reduce the need for neonatal mechanical ventilation. Although antenatal corticosteroids might not be a so-called magic bullet as a standalone vertical in
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