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Editorial opinion piece Many patients with advanced cancer w
2019-05-24
Editorial/opinion piece Many patients with advanced cancer will develop bone metastases and associated complications, including severe pain and debilitating skeletal-related events (SREs), which require radiotherapy, surgery or changes to antineoplastic regimens [1–3]. Fortunately, there are effect
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During the ACh provocation test our patient
2019-05-24
During the ACh provocation test, our patient did not complain of chest pain, ECG showed no discernible ST-T changes, and CAG demonstrated no spastic findings. These indicate that ACh evoked the J wave by its direct pharmacological actions in this case. J waves are currently recognized as a surface E
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niclosamide En el primer apartado presentamos las modificaci
2019-05-24
En el primer apartado, presentamos las modificaciones que se produjeron en los lineamentos que proponen estos organismos para la política social de la región y buscaremos mostrar que ocurrió un desplazamiento de la cuestión social entendida como pobreza niclosamide su redefinición como desigualdad.
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Los paradigmas de cosmopolitismo de Mito entraron en di
2019-05-24
Los paradigmas de cosmopolitismo de Mito entraron en diálogo con los de Jorge Luis Borges, Octavio Paz, Baldomero Sanín Cano y Alfonso Reyes; todos integraron su comité de patrocinio. Se miró atentamente la actualidad cultural de París, pero no la de la nrf, sino la que concentró Les Temps Modernes
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To more accurately map the
2019-05-24
To more accurately map the del(7q) and to search for other submicroscopic aberrations, we performed BAC-based array CGH analysis on BM from the accelerated phase. This confirmed an interstitial deletion in chromosome bands 7q22.1-q35 of maximal size 50.0Mb (Fig. 2D). The minimal region of deletion e
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br Uganda is on the verge of
2019-05-24
Uganda is on the verge of eliminating the () form of human African trypanosomiasis (HAT), commonly known as sleeping sickness. This elimination would be historic. In 2015, only four cases of this neglected tropical disease were diagnosed in the entire country. A similarly low number of cases in 2
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The time to use the
2019-05-24
The time to use the distraction–osteogenesis apparatus in children was suggested to be after infection eradication. We used the Ilizarov apparatus immediately following radical debridement to provide stability and prepare for distraction–compression osteogenesis 1 week later. Circular external fixa
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br Conclusion br Authors contribution br Competing
2019-05-23
Conclusion Authors’ contribution Competing interests Acknowledgments Case report Imatinib has radically changed prognosis in chronic-phase Chronic Myeloid Leukemia (CML), with 90% overall survival rate at 8yrs, and 40–70% of patients achieving a stable MMR [1]. Even better results hav
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In contrast to the low insertion frequency in Asian populati
2019-05-23
In SCR 7 Supplier to the low insertion frequency in Asian population for HERV-K113 (13%) and -K115 (4%) [10], we demonstrate herein high insertion frequency (89.3%) of HERV-H in the Singapore population, and observe interesting correlation between prevalence and age-standardized incidence rate of H
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Programmed death ligand PD L expression is a characteristic
2019-05-23
Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed
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Education is part of the foundation for a successful ASP
2019-05-23
Education is part of the foundation for a successful ASP. A well-designed educational program provides prescribers with updated knowledge on antimicrobial use, drug resistance, and infectious disease management. Educational interventions have been shown to improve prescribing competency, change pres
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Cancer stem cells are capable of differentiation and self
2019-05-23
Cancer stem purchase Tacrolimus are capable of differentiation and self-renewal. In 1994, CSCs were described for the first time. Hematological malignance is the best evidence to support the existence CSCs. TPC (tumor Propagating cell) is the other phrase that has been used for cancer stem cells. C
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br Las medidas que toma
2019-05-23
Las medidas que toma el gobierno argentino y que abordamos en este apartado no se comprenden disociadas de este clima transnacional que marca un rumbo y delinea objetivos comunes para definir y afrontar la cuestión social. Ya en 2003, adopta un posicionamiento público respecto order PND-1186 la te
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El eje dram tico de En la
2019-05-23
El eje dramático de En la prisión… se va desarrollando RG7388 través de los relatos que el Profesor, un militante de la vanguardia política revolucionaria cubana, sueña que, a su vez sueña, que narra a un grupo de “negros” durante un agobiante verano habanero de los años noventa. Todo sucede dentro
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br In mid close to the finish line
2019-05-22
In mid-2015, close to the finish line of the Millennium Development Goals (MDGs), Tanzania has reason to be proud. As Hoviyeh Afnan-Holmes and colleagues note in their Countdown to 2015 case study, Tanzania is on track to achieve MDG4: a two-thirds they say in child mortality. The largest gains i
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