• Previously we have demonstrated that AT

  2018-11-12

  

  Previously we have demonstrated that AT-MSCs express enzymes relevant for the intracellular metabolism of 5FU such as thymidylate synthase (TS), thymidylate phosphorylase (TP), orotate phosphoribosyltransferase (OPRT) and dihydropyrimidine dehydrogenase (DPD) (Kucerova et al., 2008). DPD rapidly deg

• In summary the EDX and WDX analyses of Ca P

  2018-11-12

  

  In summary, the EDX and WDX analyses of Ca/P ratios showed that the minerals formed in the osteogenically stimulated group (+DAG) and the control group (−DAG) were a type of calcium phosphate but not a pure HA. Furthermore, TEM and SAED revealed that the mineral formed in both groups showed similari

• JNK signaling promotes the expression of

  2018-11-12

  

  JNK signaling promotes the expression of cytoprotective genes in flies, which contributes to tissue homeostasis loss in aged guts (Biteau et al., 2008). We found that JNK activity was increased in dbr- and ptc-depleted guts, and further inhibition of JNK activity in these guts effectively suppressed

• Thus with these data we assert that small replicating

  2018-11-12

  

  Thus, with these data we assert that small replicating cells do not “become” large replicating cells upon culture expansion of BMSCs. Nor are those large cells “old”, in the sense that these cells are from earlier generations that gradually increase in cell size with time in vitro. Rather, large cel

• pmpa Genetically engineered stem cells may

  2018-11-12

  

  Genetically engineered stem cells may have an advantage for gene therapy due to their inherent migration to tumor sites (Kang et al., 2012a; Kang et al., 2012b; Kang et al., 2012d). In this study, we employed HB1.F3 human neural stem cells (hNSCs) obtained from 15week fetal telencephalon and immorta

• br Resource details br Materials and methods br Resource Tab

  2018-11-12

  

  Resource details Materials and methods Resource Table Resource details Materials and methods Verification and authentication Resource table: Resource details Materials and methods Resource details. RCM1 was shown to be pluripotent by expression of Oct 4 using immunocytochem

• In the current study we devised simple

  2018-11-09

  

  In the current study, we devised simple refinements to the conventional culture condition of Kubota et al. (2004b) that promotes utilization of glycolysis, which we have termed GO (glycolysis-optimized) conditions. To achieve this, we removed all supplementation of lipids and free fatty acids from t

• br Methods br Results br Discussion Mean birth weight

  2018-11-09

  

  Methods Results Discussion Mean birth weight was significantly higher among midwifery patients, in every moderate quality study in which it was examined (Heins et al., 1990; McLaughlin et al., 1992; Visintainer et al., 2000). Other studies have reported a birth weight gradient associated wi

• br Materials and Methods br

  2018-11-09

  

  Materials and Methods Results Discussion The present study demonstrated that both rs6435156C>T and rs1048829G>T variant genotypes in the 3′UTR of BMPR2 were associated with increased risk of COPD in a southern Chinese population. COPD smokers carrying the T variant (CT and TT) of rs6435156

• One of the most important of these sciences the

  2018-11-09

  

  One of the most important of these sciences, the branch of biology and experimental psychology known as ethology, studies animal behaviour in both controlled and natural environments and examines how animals adapt to environmental change to improve their chances of survival. Human ethology studies a

• Various cognitive domains support literacy acquisition Thus

  2018-11-09

  

  Various cognitive domains support literacy acquisition. Thus, heterogeneous cognitive fingerprints of dyslexia phenotypes exist (Heim and Grande, 2012; Ramus and Ahissar, 2012) and multiple subtypes of dyslexia have been suggested (Bosse et al., 2007), but a bona fide theory of the underlying mechan

• Treatments against TNF exhibit a remarkable

  2018-11-09

  

  Treatments against TNF-α exhibit a remarkable clinical response in some UC patients (Danese et al., 2013), but the majority of emerging selective ADAM17 inhibitors which target TNF-α shedding in human inflammatory diseases are not successful (Duffy et al., 2011). The information in the present study

• br Materials and Methods br Results br

  2018-11-09

  

  Materials and Methods Results Discussion We report that increased GRK2 levels and functionality in either luminal or basal cancer candesartan cilexetil can drive the acquisition and maintenance of tumoral proliferation and survival. Elevated GRK2 protein levels are detected in different br

• Previous family based studies did

  2018-11-09

  

  Previous family-based studies did not take into account e but the overall evidence suggested that shared environment between twins did not contribute to MDD () in line with Zeng et al. that did not identify any effect of shared environment between siblings or family members. On the other hand, indiv

• Randomization inference can be conducted by following the re

  2018-11-09

  

  Randomization inference can be conducted by following the “reasoned basis for inference” logic of Fisher (1935): because the design assumption is that the precise order of arrival of units is arbitrary, one can construct counterfactual distributions by reshuffling this order in which subjects arrive

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