• The most important contribution of

  2018-10-24

  

  The most important contribution of our study to ZIKV research is the finding of ZIKV-mediated impairment of hNSC neuronal differentiation in a cell-strain-dependent manner. Specifically, ZIKV infection significantly reduced neuronal differentiation of K054 and K048 strains but not G010. Both RNA seq

• The survival rate in the experimental

  2018-10-24

  

  The survival rate in the experimental group was 100%, and the scar area was significantly smaller compared to the control group. The animals from this group exhibited complete epithelialization of the wound surface in all cases (Fig. 4b, c). A histological examination of the scar tissue also reveale

• br Funding This work was supported by the

  2018-10-24

  

  Funding This work was supported by the Swedish Research Council for Health, Working Life and Welfare (FORTE) under Grant number 2014-0445 for Jenny Torssander, and by the University of Copenhagen for Laust H Mortensen. Body Reports of disrespectful maternity care are emerging worldwide, despi

• We have reported earlier that

  2018-10-23

  

  We have reported earlier that peripheral blood cells expressing the tyrosine kinase receptors VEGFR-2 or Tie-2 define functionally competent cell populations capable of re-endothelialization and differentiation into smooth muscle cells, the numbers of which are ≈0.8% and 2% respectively in PWB (Nowa

• Although the physiological role of CLEC in Kupffer cell acti

  2018-10-23

  

  Although the physiological role of CLEC2 in Kupffer cell activation and phagocytic activity is not completely understood, published studies support our hypothesis. Kerrigan et al., for example, generated a chimeric receptor bearing the extracellular and transmembrane domains of CLEC7a and the cytopl

• Treatment of acquired TTP involves plasma exchange PEX to pr

  2018-10-23

  

  Treatment of acquired TTP involves plasma exchange (PEX) to provide a new source of ADAMTS13. Steroids are used to target the autoimmune component of the disease. Therapy with rituximab reduces rates of recurrence (Scully et al., 2011; Westwood et al., 2013). Recombinant ADAMTS13 is currently underg

• br Methods br Results br Discussion A main health

  2018-10-23

  

  Methods Results Discussion A main health obstacle to control TB is that latent bacilli may remain viable for decades and reactivate later to cause active TB. Thus, there is a need to identify LTBI individuals and treat them to eliminate the risk of developing TB. Since there is no diagnosti

• Finally in limited studies it has been suggested that the

  2018-10-23

  

  Finally, in limited studies it has been suggested that the presence or absence of any particular comorbid anxiety disorders may alter the pattern and prognosis of bipolar disorder. For instance, Pini et al. (1997) suggested three patterns in association with anxiety and affective disorder: (i) GAD w

• br Introduction Alcohol use is one

  2018-10-23

  

  Introduction Alcohol use is one of the greatest risk factors for disease and disability (Rehm, 2011; Nutt et al., 2010; Rehm et al., 2009), and alcohol dependence (AD) seems to account for the majority of this burden (Rehm et al., 2012; Rehm et al., 2013). The risk of mortality has been shown to

• One case control study and several

  2018-10-23

  

  One case–control study and several case reports, including a total of 7 patients, suggested an association between linezolid mitochondrial toxicity and the mitochondrial ribosomal RNA polymorphisms A2706G or G3010A (Palenzuela et al., 2005; Carson et al., 2007; Velez and Janech, 2010; Del Pozo et al

• Using data gathered from to our

  2018-10-23

  

  Using data gathered from 2003 to 2013, our dose–response analysis identified greater Δage in cancer survivors and participants who died from cancer (Δage=0.5 and 2.2years, respectively) relative to cancer-free participants (Δage=−0.4years, test for trend P=0.02) (Fig. 1); Kaplan–Meier (KM) curves co

• The gene was cloned in

  2018-10-23

  

  The gene was cloned in 1990 and initial studies of the large complex gene identified only between 30 and 65% of germline mutations in clearly affected individuals (Shen et al., 1996). Furthermore, phenotype analysis in pedigrees suggested that there would be little significant genotype–phenotype cor

• br Materials and Methods br Results br

  2018-10-23

  

  Materials and Methods Results Discussion Until recently, many internal organs were believed to be sterile environments. Recent studies have however changed that view, showing that even healthy placentas consistently harbor microbial communities (Aagaard et al., 2014). This study serves to s

• In the present study the sensitivity of detection of the

  2018-10-23

  

  In the present study, the sensitivity of detection of the clinical isolates in vitro by the FcMBL ELLecSA was enhanced upon release of PAMPs by either mechanical disruption or treatment with bacteriocidal antibiotics, and this correlated with the detection of PAMPs in blood samples in both our studi

• Machine learning is a branch

  2018-10-23

  

  Machine learning is a branch of AI-based methods that we have applied to examine pathophysiological and clinical parameters as well as therapeutic outcomes in the past, whereby it outperformed standard statistical inference with datasets of as little as 28 patients (Chigutsa et al., 2015; Gumbo et a

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